代表性论文:

1、Chang Z, Jiang N, Zhang Y, Lu H, Yin J, Wahlgren M, Cheng X, Cao Y, Chen Q.The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate. Nat Commun. 2016 May 6;7:11537.

2、Zhang Y, Jiang N, Jia B, Chang Z, Zhang Y, Wei X, Zhou J, Wang H, Zhao X, YuS, Song M, Tu Z, Lu H, Yin J, Wahlgren M, Chen Q. A comparative study on the heparin-binding proteomes of Toxoplasma gondii and Plasmodium falciparum.Proteomics. 2014 Aug;14(15):1737-45.

3、Zhang Y, Jiang N, Lu H, Hou N, Piao X, Cai P, Yin J, Wahlgren M, Chen Q.Proteomic analysis of Plasmodium falciparum schizonts reveals heparin-binding merozoite proteins. J Proteome Res. 2013 May 3;12(5):2185-93.

4、Jia B, Chang Z, Wei X, Lu H, Yin J, Jiang N, Chen Q. Plasma microRNAs are promising novel biomarkers for the early detection of Toxoplasma gondii infection. Parasit Vectors. 2014 Sep 8;7:433.

5、Jia B, Lu H, Liu Q, Yin J, Jiang N, Chen Q. Genome-wide comparative analysis revealed significant transcriptome changes in mice after Toxoplasma gondii infection. Parasit Vectors. 2013 Jun 4;6:161.

6、Jiang N, Chang Q, Sun X, Lu H, Yin J, Zhang Z, Wahlgren M, Chen Q. Co-infections with Plasmodium knowlesi and other malaria parasites, Myanmar.Emerg Infect Dis. 2010 Sep;16(9):1476-8.

7、Zhang Y, Jiang N, Chang Z, Wang H, Lu H, Wahlgren M, Chen Q. The var3 genes of Plasmodium falciparum 3D7 strain are differentially expressed in infected

erythrocytes. Parasite. 2014;21:19.

8、Gang Liu, Yan Su, Mengjiao Zhou, Jixue Zhao , Tianyu Zhang ,Waqas Ahmad ,Huijun Lu, Ning Jiang, Qijun Chen, Mei Xiang, Jigang Yin *.Prevalence and molecular characterization of Giardia duodenalis isolates from dairy cattle in northeast China. Experimental Parasitology.2015,154:20-24

9、Shuai Peng , Jigang Yin, Xiaolei Liu , Boyin Jia, Zhiguang chang , Huijun Lu, Ning Jiang , Qijun Chen.First insights into the microbial diversity in the omasum and reticulum of bovine using Illumina sequencing .J Appl Genet. 2015,56(3):393-401.

10、Yin J, Qu G, Cao L, Li Q, Fetterer R, Feng X, Liu Q, Wang G, Qi D, Zhang X, Miramontes E, Jenkins M, Zhang N, Tuo W. Characterization of Neospora caninum microneme protein 10 (NcMIC10) and its potential use as a diagnostic marker for neosporosis. Vet Parasitol. 2012 Jun 8;187(1-2):28-35.

11、Zhang X, Wang Z, Su Y, Liang X, Sun X, Peng S, Lu H, Jiang N, Yin J*, Xiang M, Chen Q*. Identification and genotyping of Enterocytozoon bieneusi in China. J Clin Microbiol. 2011 May;49(5):2006-8

12、Xiao Y, Yin J, Jiang N, Xiang M, Hao L, Lu H, Sang H, Liu X, Xu H, Ankarklev J, Lindh J, Chen Q. Seroepidemiology of human Toxoplasma gondii infection in China. BMC Infect Dis. 2010 Jan 7;10:4.

13、Jiang N, Meng L, Lu HJ,Kang W, Peng S, Pan WQ,Yin JG*, Chen QJ*. Analysis of var genes cloned from a Plasmodium falciparum isolate in China. Asian Pac J Trop Med.2012;5(2):85-90.

14、Sun X, Mei M, Zhang X, Han F, Jia B, Wei X, Chang Z, Lu H, Yin J, Chen Q,Jiang N. The extracellular matrix protein mindin as a novel adjuvant elicits

stronger immune responses for rBAG1, rSRS4 and rSRS9 antigens of Toxoplasma gondii in BALB/c mice. BMC Infect Dis. 2014 Aug 4;14:429.

15、Liu X, Song Y, Jiang N, Wang J, Tang B, Lu H, Peng S, Chang Z, Tang Y, Yin J, Liu M, Tan Y, Chen Q. Global gene expression analysis of the zoonotic parasite

Trichinella spiralis revealed novel genes in host parasite interaction. PLoS Negl Trop Dis. 2012;6(8):e1794.

近三年承担主要课题:

恶性疟原虫与侵入红细胞相关的新型蛋白质及功能分析,国家自然科学基金国际合作与交流项目,编号81420108023,2015.01-2019.12。资助金额300万。

疟原虫TatD-like DNase的功能分析及与虫体致病的相关性分析,81130033,陈启军,2012.01-2016.12。资助金额240万。

微小隐孢子虫肝素结合蛋白质的鉴定和功能研究,国家自然科学基金面上项目,编号31772731,2018-2021。资助额度60万元。

胞内寄生原虫对宿主组织和细胞的嗜性及机理,“十三五”国家重点研发计划,编号2017YFD500401,2017.07-2020.12。资助额度40万元。

微小隐孢子虫跨种传播的分子机制,国家自然科学基金面上项目,编号31272549,2013.01-2016.12。资助金额80万元。

人兽共患弓形虫疫苗候选抗原与快速检测技术的研究,吉林省自然科学基金项目,项目编号20140101034JC,2014-2016,资助额度12万元。

弓形虫侵入宿主细胞相关蛋白质鉴定及新型疫苗的研究,吉林省重点科技公关项目20150204020NY,2015-2017,资助额度18万元。

 

 

授权专利:

1、可检测感染弓形虫的标识性mmu-miR-712-3p 陈启军; 姜宁; 贾博寅ZL201410072189.5

2、可检测感染弓形虫的标识性mmu-miR-217-5p 陈启军; 贾博寅; 姜宁ZL201410072202.7

3、可检测感染弓形虫的标识性mmu-miR-511-5p姜宁; 陈启军; 贾博寅ZL201410072204.6

4、一种诊断用微小隐孢子虫重组抗原 尹继刚; 高依然; 向梅; 姜宁; 陆慧君; 陈启军ZL201410011922.2

5、一种弓形虫循环抗原双抗夹心ELISA检测方法。向梅,尹继刚,王海礁,陆慧君,姜宁,陈启军ZL201010264255.0

6、可抑制恶性疟原虫侵入的抗Pf332-DBL区抗体。姜宁;陈启军;杜承;尹继刚;陆慧君ZL201210176879.6

7、一种可抑制恶性疟原虫侵入的抗Pf332-DBL区抗体。陈启军;杜承;姜宁;尹继刚;陆慧君ZL201010174866.6

科研获奖:

吉林省科学技术奖一等奖 编号:2014Z10002 日期2014.11.4

获奖项目:恶性疟原虫、日本血吸虫免疫逃避和致病的机理研究

获奖人:陈启军、姜宁、尹继刚、陆慧君、王芯蕊、常巧呈、杜承、张岩、吴闯