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孙万春

作者:时间:2025-03-05点击数:

                姓名:     孙万春

 

                     

性别:

 

           职称:副教授

 

硕导/博导:硕导

 

      最高学位:博士

 

          最高学历:博士研究生

 

  办公电话:87836711

 

邮箱:wanchunsun@jlu.edu.cn

 

 

 

详细情况

学科专业:

兽医公共卫生

研究方向:

炎症性疾病及其治疗药物发现和机制研究

讲授课程:

本科生:

硕士生:

教育经历:

1987.08-1992.07,吉林大学,生物化学,学士学位

1996.09-1999.07,吉林大学,生物化学和分子生物学,硕士学位

2001.09-2004.07,中科院上海药物研究所,药理学,博士学位

工作经历:

1992.07-1996.08,长春生物制品研究所,助理工程师

2004.12-2009.07University of Georgia, Athens, USA, Postdoc research fellow

2011.03-至今,吉林大学动物医学学院,副教授

科研项目:

 

学术论文:

(1) Zhang Y, Wang J, Jing C, Zhou MX, Jin W, Yan   X, Hou H, Shi K, Sun WC(*), Sun L(*). Purple tea water extract blocks RANKL-induced osteoclastogenesis   through modulation of Akt/GSK3β and Blimp1-Irf8 pathways. Food Funct. 2022   Aug 30;13(17):8850-8859.

(2) Cao J, Zhou MX, Chen X, Sun M, Wei C, Peng   Q, Cheng Z(*)Sun W(*), Wang H(*). Sec-O-Glucosylhamaudol Inhibits   RANKL-Induced Osteoclastogenesis by Repressing 5-LO and AKT/GSK3β Signaling.   Front Immunol. 2022 Apr 26;13:880988.

(3) Cao J, Wang S, Wei C, Lin H, Zhang C, Gao Y,   Xu Z, Cheng Z(*), Sun WC(*), Wang HB(*). Agrimophol suppresses RANKL-mediated   osteoclastogenesis through Blimp1-Bcl6 axis and prevents inflammatory bone   loss in mice. Int Immunopharmacol. 2021 Jan;90:107137.

(4) Hou H, Peng Q, Wang S, Zhang Y, Cao J, Deng   Y, Wang Y(*), Sun WC(*), Wang HB(*). Anemonin Attenuates RANKL-Induced   Osteoclastogenesis and Ameliorates LPS-Induced Inflammatory Bone Loss in   Mice via Modulation of NFATc1. Front Pharmacol. 2020 Feb   10;10:1696.

(5) Zhang Y, Wang Z, Xie X, Wang S, Wang Y, Quan   G, Wang H(*), Sun WC(*). Tatarinan T, an α-asarone-derived lignin, attenuates   osteoclastogenesis induced by RANKL via the inhibition of NFATc1/c-Fos   expression. Cell Biol Int. 2019 Dec;43(12):1471-1482.

(6)Zhang   Yuxin; Wang Zhi; Xie Xiaona; Wang Jing; Wang Yingjian; Peng Qi sheng; Zhang   Maolin; Wu Donglin; Liu Ning(*); Wang Hong bing(*)Sun   Wan chun(*)Tatarinan N inhibits osteoclast   differentiation through attenuating NF-kappa B, MAPKs and Ca2+-dependent   signaling, International   Immunopharmacology, 2018.12, 65: 199~211   

(7)Cao,   Jinjin; Lu, Qiang; Liu, Ning(#); Zhang, Yu-Xin; Wang, Jing; Zhang,   Maolin; Wang, Hong-Bing(*)Sun, Wan-Chun(*)Sciadopitysin   suppresses RANKL-mediated osteoclastogenesis and prevents bone loss in LPS-treated   mice.,International Immunopharmacology, 2017.5.30, 49:   109~117    

(8)Xu,   Xiaohan; Liu, Ning; Wang, Yingjian; Pan, Lei-chang; Wu, Donglin; Peng,   Qisheng; Zhang, Maolin; Wang, Hong-bing(*)Sun, Wan-chun(*)Tatarinan O,   a lignin-like compound from the roots of Acorus tatarinowii Schott inhibits   osteoclast differentiation through suppressing the expression of c-Fos and   NFATc1. Int Immunopharmacol, 2016.5.01, 34:   212~219    

(9)Quan,   Gui-Hua; Wang, Hongbing; Cao, Jinjin; Zhang, Yuxin; Wu, Donglin; Peng,   Qisheng; Liu, Ning(*)Sun, Wan-ChunCalycosin   Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and   NF-kappaB. Int J Mol Sci, 2015.12.10, 16(12):   29496~29507    

(10)Wang,   Yingjian; Xu, Xiaohan; Wang, Hong-bing; Wu, Donglin; Li, Xiao-ou; Peng,   Qisheng; Liu, Ning(*)Sun, Wan-chun(*)17-Hydroxy-jolkinolide   A inhibits osteoclast differentiation through suppressing the activation of   NF-kappaB and MAPKs. Int   Immunopharmacol, 2015.12.01, 29(2): 513~520 

(11)Xu,   Xiaohan; Liu, Ning; Zhang, Yu-Xin; Cao, Jinjin; Wu, Donglin; Peng, Qisheng;   Wang, Hong-Bing(*)Sun, Wan-Chun(*)The Protective   Effects of HJB-1, a Derivative of 17-Hydroxy-Jolkinolide B, on LPS-Induced   Acute Distress Respiratory Syndrome Mice. Molecules, 2016.1.11, 21(1):   77~77    

(12)Pan,   Lei-Chang; Xu, Xiao-Han; Zhang, Na-Na; Liu, Ning; Wu, Dong-Lin; Wang, Yang;   Peng, Qi-Sheng; Vandenplas, Michel; Wang, Hong-Bing(*)Sun,   Wan-Chun(*)HJB-1, a   17-hydroxy-jolkinolide B derivative, inhibits LPS-induced inflammation in   mouse peritoneal macrophages. Int Immunopharmacol, 2014.8.01, 21(2):   474~480    

(13)Chen, Wei;   Zhang, Ying-Ying; Wang, Zhuo; Luo, Xiao-Hua; Sun, Wan-Chun(*);   Wang, Hong-Bing(*)Phenolic derivatives   from Radix Astragali and their anti-inflammatory activities. Nat Prod Commun, 2014.11.01, 9(11):   1577~1580   

   

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