性别：男

职称：教授

硕导/博导：博导

最高学位：博士

最高学历：研究生

办公电话：13943051050

邮箱：duan_ming@jlu.edu.cn

详细情况

学科专业：

兽医公共卫生

研究方向：

人兽共患病（病毒）

讲授课程：

本科生：动物病毒学；动物检验检疫学

硕士生：动物病毒学；动物检验检疫学

教育经历：

2003/09 - 2007/06，中国人民解放军军事医学科学院，生物化学与分子生物学，博士。

1999/09 - 2003/07，原中国人民解放军军需大学，动物营养与饲料科学，硕士。

1992/09 - 1996/07，中国海洋大学，水产养殖，学士。

工作经历：

2016/09 - 至今，吉林大学，人兽共患病研究所，教授

2010/04 - 2012/04，美国内布拉斯加州医学中心，博士后

2009/09 - 2016/09，吉林大学，人兽共患病研究所，副教授

2007/07 - 2009/08，吉林大学，人兽共患病研究所，讲师

2001/10 - 2004/08，原中国人民解放军军需大学，中心实验室（基因芯片实验室），讲师

1996/07 - 2001/09，原中国人民解放军军需大学，畜牧兽医学院，助教

科研项目：

在研（主持）

Ÿ 吉林省自然基金面上项目“宿主长链非编码RNA-NR_002812在甲型流感病毒复制中作用的机制研究（20230101147JC）”

Ÿ 国家自然基金面上项目 “宿主长链非编码RNA-GBP1P1抑制病毒复制作用的机制研究（31970154）”

已完成（主持）

Ÿ 国家自然基金青年基金 “流感病毒感染相关宿主microRNA的鉴定及功能分析（30800823）”

Ÿ 国家自然基金面上项目 “狂犬病病毒感染相关宿主miRNA的鉴定及功能分析（31172337）”

Ÿ “省部共建国家重点实验室开放课题（中国人民解放军军事医学科学院）”

Ÿ “吉林大学国家杰出青年基金后备人选培育计划”资助。

学术论文：

以通讯及第一作者发表的论文

Ÿ Guo Y, Yu X, Su N, Shi N, Zhang S,   Zhang L, Yang L, Zhao L, Guan Z, Zhang M, Duan M^*. Identification   and characterization of circular RNAs in the A549 cells following Influenza A   virus infection. Vet Microbiol. 2022 Apr;267:109390.

Ÿ Shi N, Zhang L, Yu X, Zhu X, Zhang   S, Zhang D, Duan M^*. Insight Into an Outbreak of Canine   Distemper Virus Infection in Masked Palm Civets in China. Front Vet Sci. 2021   Nov 3;8:728238.

Ÿ Qi Wang; Daining Zhang; Wenjing   Feng; Yidi Guo; Xiaoning Sun; Maolin Zhang; Zhenhong Guan;Ming Duan^*   Long non‐coding RNA TSPOAP1 antisense RNA 1 negatively modulates type I IFN   signaling to facilitate influenza A virus replication. Journal of Medical   Virology, 2022   Feb;94(2):557-566.

Ÿ Ning Shi^#; Shu Zhang^#;   Yidi Guo^#; Xiuhua Yu; Weizheng Zhao; MaolinZhang; Zhenhong Guan; Ming Duan^*_。CircRNA_0050463 promotes influenza A virus replication by sponging   miR-33b-5p to regulate EEF1A1. Veterinary Microbiology. 2021 Mar,   (254): 108995.

Ÿ Sun xiaoning^#; Feng   wenjing^#; Guo yidi^#; Wang Qi; Dong chunyan; Zhang   maolin; Guan zhenhong;Duan ming^*_. MCPIP1   attenuates the innate immune response to influenza A virus by suppressing   RIG-I expression in lung epithelial cells. Journal of Medical Virology,   2018, 90(2): 204-211.

Ÿ Qu Xinyan^#; Ding   Xiaoran^#;Duan ming^#; Yang jing; Lin ruxian; Zhou   zhe; Wang shengqi^*.Influenza   virus infection induces translocation of apoptosis-inducing factor (AIF) in   A549 cells: role of AIF in apoptosis and viral propagation. Archives of   Virology, 2017, 162(3): 669-675.

Ÿ Feng wenjing^#; Sun   xiaoning^#; Shi ning; Zhang maolin; Guan zhenhong;Duan ming^*.Influenza   a virus NS1 protein induced A20 contributes to viral replication by   suppressing interferon-induced antiviral response. Biochemical and   Biophysical Research Communications, 2017, 482(4): 1107-1113.

Ÿ Dong chunyan; Sun xiaoning; Guan   zhenhong; Zhang maolin;Duan ming^*.Modulation of influenza A virus replication by microRNA-9 through   targeting MCPIP1. Journal of Medical Virology, 2017, 89(1): 41-48.

Ÿ Sun xiaoning; Shi ning; Li ying;   Dong chunyan; Zhang maolin; Guan zhenhong;Duan ming^*.Quantitative   Proteome Profiling of Street Rabies Virus-Infected Mouse Hippocampal   Synaptosomes. Current Microbiology, 2016, 73(3): 301-311.

Ÿ Zhang huanhuan; Yu hongmin; Wang   Jiahui; Zhang maolin; Wang X; Ahmad Waqas; Duan ming^*; Guan   zhenhong^*.The BM2   protein of influenza B virus interacts with p53 and inhibits its   transcriptional and apoptotic activities. Molecular and Cellular   Biochemistry, 2015, 403(1-2): 187-197.

Ÿ Zhang Xiaoyang; Dong Chunyan; Sun   Xiaoning; Li Zhongyi; Zhang Maolin; Guan Zhenhong;Duan Ming^*.Induction   of the cellular miR-29c by influenza virus inhibits the innate immune   response through protection of A20 mRNA. Biochemical and Biophysical   Research Communications, 2014, 450(1): 755-761.

Ÿ Shi ning; Zhang xiaoyang; Dong chunyan;   Hou jinli; Zhang maolin; Guan zhenhong; Li zhongyi;Duan ming^*.Alterations   in microRNA expression profile in rabies virus-infected mouse neurons

Ÿ Acta Virologica, 2014, 58(2): 120-127.

Ÿ Duan ming; Yao honghong; Cai yu; Liao ke; Seth Pankaj; Buch Shilpa^*.HIV-1 Tat Disrupts CX3CL1-CX3CR1 Axis in Microglia via   the NF-kappa B-YY1 Pathway. Current HIV Research, 2014, 12(3):   189-200.

Ÿ Duan ming; Yao honghong; Hu guoku; Chen xianming; Amie K. Lund; Shilpa Buch^*.HIV Tat induces expression of ICAM-1 in HUVECs: implications   for miR-221/-222 in HIV-associated cardiomyopathy. PLos One, 2013,   8(3): e60170.

Ÿ Yao honghong^#;Duan   ming^#; Yang lu; Shilpa Buch^*.Nonmuscle myosin light-chain kinase mediates microglial   migration induced by HIV Tat: Involvement of beta 1 integrins. The FASEB   Journal,

Ÿ Guan zhenhong; Shi ning; Song yan;   Zhang xiaoyang; Zhang maolin; Duan ming^*.Induction of the cellular microRNA-29c by influenza   virus contributes to virus-mediated apoptosis through repression of   antiapoptotic factors BCL2L2. Biochemical and Biophysical Research   Communications, 2012, 425(3): 662-667.

Ÿ Yao honghong^#;Duan   ming^#; Yang lu; Shilpa Buch^*.Platelet-Derived Growth Factor-BB Restores Human   Immunodeficiency Virus Tat-Cocaine-Mediated Impairment of Neurogenesis: Role   of TRPC1 Channels. Journal of Neuroscience, 2012, 32(29): 9835-9847.

Ÿ Yao honghong^#;Duan   ming^#; Hu guoku; Shilpa Buch^*.Platelet-Derived Growth Factor B Chain Is a Novel   Target Gene of Cocaine-Mediated Notch1 Signaling: Implications for   HIV-Associated Neurological Disorders. Journal of Neuroscience, 2011,   31(35): 12449-12454.

Ÿ Yao honghong^#;Duan ming^#; Shilpa Buch^*.Cocaine-mediated induction of platelet-derived growth   factor: implication for increased vascular permeability.Blood, 2011,   117(8): 2538-2547.

著作教材：

获奖情况：

社会兼职：